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Figure c14/f001
Figure 14.1
An overview of the relationship between the dose of any particular drug and therapeutic outcome. Multiple, often interdependent, factors impact at cri...
Figure c14/f002
Figure 14.2
Swiss cheese model to illustrate the cumulative effect of multiple failures (holes) in defence mechanisms that ultimately translate drug hazard into a...
Figure c14/f003
Figure 14.3
An overview of the phases of drug development from discovery through to licensing and post‐marketing surveillance (phase IV). Toxicity, failed efficac...