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Figure 14.1
An overview of the relationship between the dose of any particular drug and therapeutic outcome. Multiple, often interdependent, factors impact at cri...
Figure 14.2
Swiss cheese model to illustrate the cumulative effect of multiple failures (holes) in defence mechanisms that ultimately translate drug hazard into a...
Figure 14.3
An overview of the phases of drug development from discovery through to licensing and post‐marketing surveillance (phase IV). Toxicity, failed efficac...